COGNITIVE, MOOD & SLEEP · CAS 62568-57-4

DSIP 5mg

Naturally occurring nonapeptide first isolated in 1977. Characterized by delta-frequency EEG activity induction and studied for neuromodulatory properties across sleep regulation, stress response, and CNS signaling.


Purity ≥99%
Mol. Weight 848.81 g/mol
Form Lyophilized white powder

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  • Cold-chain shipping 2–8°C
  • Batch CoA · HPLC + mass-spec verified
  • cGMP manufactured in Houston, TX

Product Background

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first isolated in 1977 by the research group of Dr. Marcel Monnier and Dr. Guido Schoenenberger at the University of Basel in Switzerland. The peptide was identified during electrophysiological experiments on rabbits in which cerebral venous blood from sleep-induced animals was infused into recipient subjects, where it produced a characteristic increase in delta-frequency electroencephalographic activity. DSIP has been studied in laboratory research for nearly five decades for its neuromodulatory properties, with documented investigation across sleep regulation, stress response, and central nervous system signaling.

About the Product

Each vial contains 5 mg of DSIP supplied as a lyophilized white powder at ≥99% purity, with 10 vials per package. As a small nonapeptide, DSIP is highly soluble after reconstitution with bacteriostatic or sterile water. The compound is used in controlled laboratory settings investigating its broad-spectrum neuromodulatory effects.

Applications

  • Sleep architecture and slow-wave (delta) sleep research in animal models
  • Circadian rhythm and pineal-axis investigations
  • Studies of the hypothalamic-pituitary-adrenal (HPA) axis and stress response
  • Neuroprotection research in models of oxidative stress
  • Research on opioid withdrawal models and dependence biology
  • Investigations of body temperature regulation and thermoregulatory pathways
  • Studies of antinociception and central pain modulation