Synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed as an analog of pineal-derived Epithalamin. Investigated for telomerase activity, telomere length, and longevity in preclinical models.
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Dr. Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology in Russia. The compound was designed as a synthetic analog of the natural polypeptide Epithalamin, which Khavinson's group originally extracted from the pineal gland of cattle in the 1980s. Russian gerontological research has investigated Epithalon for several decades, with reported studies examining its effects on telomerase enzyme activity, telomere length, melatonin secretion patterns, and lifespan in laboratory animal models. Epithalon belongs to a broader class of compounds known as "peptide bioregulators," which were extensively studied within Soviet and post-Soviet gerontology research programs.
Each vial contains 10 mg of Epithalon supplied as a lyophilized white powder at ≥99% purity, with 10 vials per package. As a short tetrapeptide, Epithalon dissolves readily upon reconstitution with bacteriostatic or sterile water. The 10mg vial is the standard format for most laboratory protocols.
| Internal SKU | 100245 |
|---|---|
| Strength | 10 mg per vial |
| Package | 10 vials per box |
| Form | Lyophilized white powder |
| Purity | ≥99% |
| CAS Number | 307297-39-8 |
| Molecular Formula | C14H22N4O9 |
| Molecular Weight | 390.35 g/mol |
| Amino Acid Sequence | Ala-Glu-Asp-Gly (tetrapeptide, 4 amino acids) |
| Also Known As | Epitalon, Epithalone |
| Storage | Store lyophilized powder at -20°C; reconstituted solution at 2–8°C. Protect from light. |
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This product is for research use only. Not intended for human or veterinary therapeutic use. Must be handled by qualified researchers in compliance with all applicable regulations. Not for resale.