ANTI-AGING & LONGEVITY · CAS 307297-39-8

Epithalon 10mg

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed as an analog of pineal-derived Epithalamin. Investigated for telomerase activity, telomere length, and longevity in preclinical models.


Purity ≥99%
Mol. Weight 390.35 g/mol
Form Lyophilized white powder

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  • Cold-chain shipping 2–8°C
  • Batch CoA · HPLC + mass-spec verified
  • cGMP manufactured in Houston, TX

Product Background

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Dr. Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology in Russia. The compound was designed as a synthetic analog of the natural polypeptide Epithalamin, which Khavinson's group originally extracted from the pineal gland of cattle in the 1980s. Russian gerontological research has investigated Epithalon for several decades, with reported studies examining its effects on telomerase enzyme activity, telomere length, melatonin secretion patterns, and lifespan in laboratory animal models. Epithalon belongs to a broader class of compounds known as "peptide bioregulators," which were extensively studied within Soviet and post-Soviet gerontology research programs.

About the Product

Each vial contains 10 mg of Epithalon supplied as a lyophilized white powder at ≥99% purity, with 10 vials per package. As a short tetrapeptide, Epithalon dissolves readily upon reconstitution with bacteriostatic or sterile water. The 10mg vial is the standard format for most laboratory protocols.

Applications

  • Telomere biology and telomerase activity research in cell culture
  • Cellular senescence and replicative aging studies
  • Pineal gland function and melatonin secretion research
  • Circadian rhythm and chronobiology investigations
  • Studies of antioxidant defense systems and oxidative stress markers
  • Aging biomarker research in animal longevity models
  • Investigations of reproductive aging and gonadal function in preclinical models